Samantha was born on April 28, 1987 in Chennai, Tamil Nadu, India.

Her full name is Samantha Ruth Prabhu.

Samantha is a trained belly dancer and has also learnt Kathak & Bharatanatyam.

She was a very bright student and used to top in school exams.

She completed her schooling from Holy Angels Anglo-Indian Higher Secondary School.

Samantha is an animal lover and has two pet dogs.

She was married to actor Naga Chaitanya, who was also her co-star in several films.